For many health care workers in South Africa, access to information on medicine availability is vital to adequately service the health care needs of their patients. The United States Agency for International Development (USAID)-funded Global Health Supply Chain Program – Technical Assistance (GHSC-TA) has been collaborating with the South African National Department of Health (NDoH) since 2016 to improve access to, and availability of medicine through the development of the National Surveillance Centre (NSC).